王建辉

· 职称：教授

· 出生年月：

· 专业：有机化学，金属有机化学

· Email：wjh@tju.edu.cn

· 课题组网址: http://tj.teacher.360eol.com/teacherBasic/preview?teacherId=3033

研究方向

1.有机合成和催化机理研究：研究金属有机化学基本理论，为设计、合成用于构建高分子和有机转化的高效催化剂提供指导。目前烯烃复分解反应催化剂的合成与催化研究是我们的研究重点。

2.有机合成方法与试剂：建立、发展有机金属配合物催化的有机合成方法， 包括碳氢键活化反应、碳碳键活化反应。

学习与工作经历

2005年-至今     天津大学理学院化学化学系，教授

2004年-2005年   南方卫理公会大学，博士后

2003年-2004年   佛罗里达大学，博士后

2002年-2003年   南方卫理公会大学，博士后

2001年-2002年   北伊利诺伊大学，访问学者

1997年-2004年  吉林大学化学系，讲师

1995年-1997年  吉林大学化学系，助教

1995年-1999年  吉林大学化学系，博士

1992年-1995年  吉林大学化学系，硕士

代表性工作

王建辉教授主要从事烯烃聚合、高效烯烃复分解催化剂的设计合成与催化反应，基于碳碳键活化的反应研究方向。已在相关研究领域发表包括Angew. Chem., Int. Ed., OL, Adv. Synth. Catal., J. Org. Chem., Organometalics 等在内的国际知名学术期刊上发表70余篇高水平研究论文，授权5项发明专利，完成4项国家自然科学基金和7项工业课题研究，主持在研1项国家自然科学基金。

主持或参与的科研项目

2021.01-2024.12主持国家自然科学基金（含类卡宾配体的钌烯烃复分解催化剂合成与催化研究 22071177）63万元

2016.01-2019.12主持国家自然科学基金（高效Z-选择性钌卡宾烯烃复分解催化剂的合成与催化研究 21572155）65万元

2014.01-2017.12主持国家自然科学基金（内离子对型烯烃复分解催化剂的合成与催化研究21372175）80万元

2011.01-2013.12主持国家自然科学基金（新型钌烯烃复分解催化剂的合成与催化研究 21072149）35万元

2009.01-2011.12主持国家自然科学基金（可控功能化钌卡宾烯烃复分解催化剂合成与催化研究20872108）30万元

代表性论文

1. Peng Ma, Yuhang Wang, Jianhui Wang*, Ning Ma. LiN(SiMe₃)₂/KOtBu-promoted synthesis of isoquinolone derivatives from 2-methylaryl aldehydes and nitriles. The Journal of Organic Chemistry, 2023, 88(11): 7425-7430

2. Peng Ma, Yuhang Wang, Jianhui Wang*, Ning Ma. Copper-catalyzed synthesis of quinazolines via cascade cyclization/ hydrodehalogena-tion. New Journal of Chemistry, 2023, 49(19): 9377-9382.

3. Yuhang Wang, Peng Ma, Ning Ma, Jianhui Wang*. Ligand-controlled nickel-catalyzed reactions of benzocyclobutenones with alkynyltrifluoroborates: Diverse construction of polysubstituted naphthols. Organic Letters, 2023, 25(19): 3527-3532.

4. Peng Ma, Jiaren Zhang, Xiaqian Wu, Jianhui Wang*. Ruthenium metathesis catalysts with imidazole ligands. Catalysts, 2023, 13(2): 276-284.

5. Peng Ma, Yuhang Wang, Jianhui Wang*. Copper-catalyzed domino three-component benzannulation: Access to isoquinolines. Organometallics, 2022, 41(16): 2235-2239.

6. Zhenzhu Hu, Peng Ma, Ning Ma, Jianhui Wang*. FeCl₃-catalyzed synthesis of tanshinlactone analogues from 1H-indene-1,2,3-triones and alkynes. The Journal of Organic Chemistry, 2022, 87(16): 10982-10989.

7. Zhenzhu Hu, Yuhang Wang, Peng Ma, Jianhui Wang*, Guiyan Liu. Decarbonyl-ative cycloaddition of 1H-indene-1,2,3-trione and norbornene via rhodium(I)-catalyzed carbon-carbon bond cleavage. New Journal of Chemistry, 2022, 46(23): 11108-11117. 

8. Zhenzhu Hu, Yuhang Wang, Peng Ma, Xiaqian Wu, Jianhui Wang*. Nickel(0)-catalyzed decarbonylative cross-coupling of aromatic esters with arylboronic acids via chelation assistance. ACS omega, 2022, 7(25), 21537–21545.

9. Xiaqian Wu, Peng Ma, Jianhui Wang*. Copper-catalyzed direct synthesis of arylated 8-aminoquinolines through chelation assistance. Applied Organometallic Chemistry, 2022, 36(4)

10. Tao Wang, Xiaobo Yu, Huiqing Zhang, Shutao Wu, Weijie Guo, Jianhui Wang*.  Synthesis and evaluation of ruthenium 2-alkyl-6-mercaptophenolate catalysts for olefin metathesis. Applied Organometallic Chemistry, 2019, 33(7): 0-e4939. 

11. Tao Wang, Qingxiao Xie, Weijie Guo, Shutao Wu, Huiqing Zhang, Jianhui Wang*, Botao Wu. A 3,4-dimercapto-3-cyclobutene-1,2-dione-chelated ruthenium carbene catalyst for Z-stereoretentive/stereoselective olefin metathesis. Dalton Transactions, 2019, 48(19): 6473-6483. 

12. Guiyan Liu*, Fangwai Han, Chengxin Liu, Hongli Wu, Yongfei Zeng, Rongjiao Zhu, Xia Yu, Shuang Rao, Genping Huang*, Jianhui Wang*. A highly active catalyst system for suzuki-miyaura coupling of aryl chlorides Organometallics, 2019, 38(7): 1459-1467. 

13. Tao Wang, Botao Wu*, Weijie Guo, Shutao Wu, Huiqing Zhang, Yanfeng Dang, Jianhui Wang*. Synthesis, catalysis, and DFT study of a ruthenium carbene complex bearing a 1,2-dicarbadodecaborane (12)-1,2-dithiolate ligand. Dalton Transactions, 2019, 48(8): 2646-2656. 

14. Tao Wang, Qingxiao Xie, Weijie Guo, Shutao Wu, Huiqing Zhang,  Jianhui Wang*. Synthesis and evaluation of naphthalene-1, 8-dithiolate chelating ruthenium carbene catalyst for Z-stereoretentive olefin metathesis. Journal of Organometallic Chemistry, 2019, 880: 62-67.

15. Xiaobo Yu, Shudong Geng, Guanchen Liu, Weijie Guo, Jianhui Wang*. Efficient indenones synthesis via iridium -catalyzed decarboxylative annulation between 2-oxo-2-phenylacetic acids and alkynes. Journal of Organometallic Chemistry, 2019, 879: 139-143. 

16. Shutao Wu, Siyuan Luo, Weijie Guo, Tao Wang, Qingxiao Xie, Jianhui Wang*, Guiyan Liu*. Direct conversion of ethyl ketone to alkyl ketone via chelation assisted rhodium(I)-catalyzed carbon−carbon bond cleavage: Ligands play an important role in the inhibition of βhydrogen elimination. Organometallics, 2018, 37(7): 2335-2341. 

17. Weijie Guo, Shutao Wu, Tao Wang, Qingxiao Xie, Yulian Duan, Siyuan Luo, Jianhui Wang*, Xiaobo Yu. Rhodium-catalyzed decarbonylative cycloadditions of 1H-indene-1,2,3-triones and alkynes via direct C–C bond activation: divergent synthesis of indenones and quinones. Organic Chemistry Frontiers, 2018, 5(4): 1613-1621. 

18. Qingxiao Xie, Tao Wang, Shutao Wu, Weijie Guo, Huiqing Zhang, Jianhui Wang*. A stable ruthenium complex bearing a 1,2-dicarbadodecaborane(12)- 1,2-dithiolate ligand and its activation for olefin metathesis. Journal of Organometallic Chemistry, 2018, 865: 95-99.

19. Tao Wang, Qingxiao Xie, Weijie Guo, Shutao Wu, Huiqing Zhang, Jianhui Wang*. Synthesis and evaluation of naphthalene-1, 8-dithiolate chelating ruthenium carbene catalyst for Z-stereoretentive olefin metathesis. Journal of Organometallic Chemistry, 2018, 880: 62-67. 

20. Shutao Wu, Weijie Guo, Tao Wang, Qingxiao Xie, Jianhui Wang*, Guiyan Liu. Formation of tertiary alcohol via chelation-assisted nickel(II)-catalyzed addition of arylboronic acids to unactivated 1-(quinolin-8-yl)ethan-1-one. Advanced Synthesis & Catalysis, 2018, 360: 4533-4542.