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副教授

聂晶

  • 职称:副教授
  • 出生年月:
  • 专业:有机化学
  • Email:niejing1121@126.com
  • 课题组网址:
研究方向

研究方向1:有机氟化学

研究方向2:不对称合成

研究简历

2004/09~2009/07:天津大学理学院,博士,导师:马军安教授

2009/07~2012/12:天津大学理学院,讲师

2012/12~至今:天津大学理学院,副教授

代表性论文与著作

[1] Zhang Ke-Feng, Nie Jing, Guo Ran, Zheng Yan, Ma Jun-An*, Chiral Phosphoric Acid-Catalyzed Asymmetric Aza-Friedel-Crafts Reaction of Indoles with Cyclic N-Acylketimines: Enantioselective Synthesis of Trifluoromethyldihydroquinazolines, Adv. Synth. Catal. 355(17), 3497-3502, 2013.

[2] Li Feng, Nie Jing, Sun Long, Zheng Yan, Ma Jun-An*, Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles, Angew. Chem., Int. Ed. 52(24),6255-6258, 2013.

[3] Yuan Hai-Na, Wang Shuai, Nie Jing, Meng Wei, Yao Qing-Wei, Ma Jun-An*, Hydrogen-Bond-Directed Enantioselective Decarboxylative Mannich Reaction of -Ketoacids with Ketimines: Application to the Synthesis of Anti-HIV Drug DPC083, Angew. Chem., Int. Ed. 52(14), 3869-3873, 2013.

[4] Wu Jun-Wei, Li Feng, Zheng Yan, Nie Jing*, DABCO-mediated one-pot sequential transformation:convenient access to fluorinated 1H-pyrazol-5(4H)-ones, Tetrahedron Lett. 53(36), 4828-4831, 2012.

[5] Liu Cui-Bo, Meng Wei, Li Feng, Wang Shuai, Nie Jing, Ma Jun-An*, A Facile Parallel Synthesis of Trifluoroethyl-Substituted Alkynes, Angew. Chem., Int. Ed. 51(25), 6227-6230, 2012.

[6] Nie Jing, Hua Ming-Qing, Xiong Heng-Ying, Zheng Yan, Ma Jun-An*, Asymmetric phase-transfer-catalyzed conjugate addition of glycine imine to exocyclic alfa, beta-unsatutrated ketones: construction of polycyclic imines containing three stereocenters, J. Org. Chem. 77(9), 4209-4216, 2012.

[7] Li Feng, Nie Jing, Wu Jun-Wei, Zheng Yan, Jun-An Ma*, Stereoselective synthesis of fluorinated 2,3-dihydroquinolin-4(1H)-ones via a one-pot multistep transformation, J. Org. Chem. 77(5), 2398-2406, 2012.

[8] Wang Lian, Meng Wei, Zhu Chuan-Le, Zheng Yan, Nie Jing, Ma Jun-An*, The long-arm effect: influence of axially chiral phosphoramidite ligands on the diastereo- and enantioselectivity of the tandem 1,4-addition/fluorination, Angew. Chem., Int. Ed. 50(40), 9442-9446, 2011.

[9] Nie Jing, Li Xiao-Juan, Zheng Dong-Hua, Zhang Fa-Guang, Cui Shumin, Jun-An Ma*, Chiral bifunctional thiourea-catalyzed enantioselective aldol reaction of trifluoroacetaldehyde hemiacetal with aromatic ketones, J. Fluorine Chem. 132(7), 468-473, 2011.

[10] Zhu Chuan-Le, Zhang Fa-Guang, Meng Wei, Nie Jing, Cahard Dominique, Ma Jun-An*, Enantioselective base-free electrophilic amination of benzofuran-2(3H)-ones: catalysis by binol-derived P-spiro quaternary phosphonium salts, Angew. Chem., Int. Ed. 50(26), 5869-5872, 2011.

[11] Zhang Guang-Wu, Meng Wei, Ma Hai, Nie Jing, Zhang Wen-Qin, Ma Jun-An*, Catalytic enantioselective alkynylation of trifluoromethyl ketones: pronounced metal fluoride effects and implications of zinc-to-titanium transmetallation, Angew. Chem., Int. Ed. 50(15), 3538-3542, 2011.

[12] Nie Jing, Guo Hong-Chao, Cahard Dominique, Ma Jun-An*, Asymmetric construction of stereogenic carbon centers featuring a trifluomethyl group from prochiral trifluoromethylated substrates, Chem. Rev. 111(2), 455-529, 2011.

[13] Nie Jing, Zhang Guang-Wu, Wang Lian, Zheng Dong-Hua, Zheng Yan, Ma Jun-An*, Chiral Brnsted Acid-Catalyzed Enantioselective Arylation of Ethyl Trifluoroacetoacetate and Ethyl Trifluoropyruvate, Eur. J. Org. Chem., 3145-3149. 2009

[14] Nie Jing, Zhang Guang-Wu, Wang Lian, Fu AiPing, Zheng Yan, Ma Jun-An*, A Perfect Double Role of CF3 Groups in Activating Substrates and Stabilizing Adducts: the Chiral Brnsted Acid-Catalyzed Direct Arylation of Trifluoromethyl Ketones, Chem. Commun., 2356-2358. 2009

[15] Nie Jing, Zhu Hong-Wei, Cui Han-Feng, Hua Ming-Qing, Ma Jun-An*, Catalytic Stereoselective Synthesis of Highly Substituted Indanones via Tandem Nazarov Cyclization and Electrophilic Flurination Trapping, Org. Lett., 9, 3053-3056. 2007

主要论著

1、 《仪器分析》,刘宇主编,天津大学出版社,2010年

2、 《有机化学简明教程》,郑艳主编,高等教育出版社

荣誉和奖励

1、 2011年,天津市优秀博士论文,“催化立体选择性合成含氟有机化合物的反应研究”,

2、 2012年,被授予“北洋学者-青年骨干教师”称号

讲授主要课程

1、 高等有机化学

2、 基础有机化学实验

3、 精细合成化学实验

正在承担项目

1、项目负责人:国家自然科学基金面上项目“仿生启发下基于β-酮酸催化脱羧反应在有机合成中的应用拓展与深入”,85万,批准号:21472137, 起止时间:2015年1月~2018年12月

2、项目负责人:天津市科委青年基金项目“新型手性亲电三氟甲基化试剂的设计合成及其应用”,6万,批准号:2014FQ-0028,起止时间:2014年4月~2017年3月

已完成项目

项目负责人:国家自然科学基金青年项目“基于潜手性三氟甲基酮及其衍生物的催化不对称转化反应研究”,19万,

批准号:21002068,起止时间:2011年1月至2013年12月,已结题。

地址:天津市津南区雅观路135号 邮编:300350

电话:022-27406577,27403637

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