姓名: 黄跟平
职称: 教授,博士生导师
专业:物理有机化学、计算化学、人工智能
办公室:北洋园校区51教学楼432室
实验室:北洋园校区51教学楼443室
邮箱:gphuang@tju.edu.cn
课题组主页: https://www.x-mol.com/groups/gphuang
学习与工作简历:
2020.07-至今:天津大学化学系(教授)
2014.12-2020.06:天津大学化学系(副教授)
2011.08-2014.12:瑞典斯德哥尔摩大学(博士后,Fahmi Himo教授课题组)
2009.09-2011.03:温州大学(访问研究生,夏远志教授课题组)
2006.09-2011.07:中国科学院青海盐湖研究所(博士,李亚红教授课题组)
2002.09-2006.07:合肥工业大学(学士)
二、研究方向:
课题组主要使用商用量化软件对有机化学和金属有机化学反应进行理论计算研究,通过对实验中难以观察到的中间体和过渡态的结构优化和能量计算,在分子水平层面上理解化学反应,在确定反应机理的基础之上探讨调控反应活性和选择性的规律,并结合人工智能和大数据预测设计新的反应体系以及使用实验手段加以验证。
三、研究生招生情况:
每年计划招收硕士研究生 2名,博士研究生1名,感兴趣的同学可以直接邮件咨询或者访问课题组主页直接与组内学生了解情况。
四、代表性成果(共发表论文70余篇,详细列表请访问课题组主页):
1. X. Yan, M. Liu, D. Pan, Q. Wang, Q. Tang, Y.-M. Dai, P. Hu, B.-Q. Wang, G. Huang,* F. Song*. Diastereo- and Enantioselective Synthesis of Tetracyclic Cycloheptanols through (4+3) Annulation via C−C/C−H Activation Cascade. Angew. Chem. Int. Ed. 2024, 63, e202317433.
2. B. Shen, D. Pan, W. Xie, X.-X. Li, S. Yu,* G. Huang,* X. Li*. Rhodium-Catalyzed Enantioselective Formal [4+1] Cyclization of Benzyl Alcohols and Benzaldimines: Facile Access to Silicon-Stereogenic Heterocycles. Angew. Chem. Int. Ed. 2024, 63, e202315230.
3. W. Wang, X. Yan, F. Ye, S. Zheng, G. Huang*, W. Yuan*. Nickel/photoredox Dual-Catalyzed Regiodivergent Aminoalkylation of Unactivated Alkyl Halides. J. Am. Chem. Soc. 2023, 145, 23385-23394.
4. P. Wang, H. Wu, X.-P. Zhang, G. Huang,* R. H. Crabtree,* X. Li*. Sigma-Bond Metathesis as an Unusual Asymmetric Induction Step in Rhodium-Catalyzed Enantiodivergent Synthesis of C-N Axially Chiral Biaryls. J. Am. Chem. Soc. 2023, 145, 8417-8429.
5. T. Guo, Y. Lin, D. Pan, X. Zhang, W. Zhu, X.-M. Cai,* G. Huang,* H. Wang, D. Xu, F. E. Kühn, B. Zhang,* T. Zhang*. Towards bioresource-based aggregation-induced emission luminogens from lignin β-O-4 motifs as renewable resources. Nat. Commun. 2023, 14: 6076.
6. Y. Wang, X. Zhu, D. Pan, J. Jing, F. Wang,* R. Mi, G. Huang,* X. Li*. Rhodium-Catalyzed Enantioselective and Diastereodivergent Access to Diaxially Chiral Heterocycles. Nat. Commun. 2023, 14: 4661.
7. X. Zhu, H. Wu, Y. Wang, G. Huang,* F. Wang*, X. Li. Rhodium-Catalyzed Annulative Approach to N-N Axially Chiral Biaryls via C-H Activation and Dynamic Kinetic Transformation. Chem. Sci. 2023, 14, 8564-8569.
8. Q. Guan, Z. Shen, G. Huang,* C. Zhang*. Ni-Catalyzed Highly Regio- and Stereo-selective Diborylative Cyclization of 1,6-Enynes with Diboron Reagent. Sci. China Chem. 2023, 64, DOI: 10.1007/s11426-023-1813-3.
9. H. Wu, L. Hu, Y. Shi, Z. Shen, G. Huang*. Computational Insights into Palladium/Boron-Catalyzed Allylic Substitution of Vinylethylene Carbonates with Water: Outer-Sphere versus Inner-Sphere Pathway and Origins of Regio- and Enantioselectivities. ACS Catal. 2022, 12, 2722.
10. R.-H. Wang, W.-W. Xu, H. Wu, Y. Li, J.-F. Li, T. Zhang, G. Huang,* M. Ye*. Ni-catalyzed Benzylic β-C(sp3)−H Bond Activation of Formamides. Nat. Commun. 2022, 13, 7892.
11. J.-F. Li, D. Pan, H.-R. Wang, T. Zhang, Y. Li, G. Huang,* M. Ye*. Enantioselective C2‒H Alkylation of Pyridines with 1,3-Dienes via Ni‒Al Bimetallic Catalysis. J. Am. Chem. Soc. 2022,144, 18810.
12. J. Niu, H. Wu, C. Niu, G. Huang*, C. Zhang*. Palladium and Amino Acid Co-Catalyzed Highly Regio- and Enantio-Selective Hydroarylation of Unbiased Alkenes. ACS Catal. 2022, 12, 8667.
13. J. Wu, H. Wu, X. Li, X. Liu, Q. Zhao, G. Huang*, C. Zhang*. Copper-Catalyzed Highly Selective Protoboration of CF3-Containing 1,3-Dienes. Angew. Chem. Int. Ed. 2021, 60, 20376.
14. M. Zhang, H. Wu, J. Yang, G. Huang*. A Computational Mechanistic Analysis of Iridium-Catalyzed C(sp3)-H Borylation Reveals a One-Stone-Two-Birds Strategy to Enhance Catalytic Activity. ACS Catal. 2021, 11, 4833.
15. L. Hu, A. Cai, Z. Wu, A. W. Kleij*, G. Huang*. A Mechanistic Analysis of the Pd-Catalyzed Formation of Branched Allylic Amines reveals the Origin of the Regio- and Enantioselectivity through a Unique Inner-Sphere Pathway. Angew. Chem. Int. Ed. 2019, 58, 14694.
16. G. Huang*, P. Liu*. Mechanism and Origins of Ligand-Controlled Linear versus Branched Selectivity of Iridium-Catalyzed Hydroarylation of Alkenes. ACS Catal. 2016, 6, 809.
17. G. Huang, Y. Xia*. Catalyst-Controlled C-C σ Bond Cleavages in Metal Halide-Catalyzed Cycloisomerization of 3-Acylcyclopropenes via a Formal 1,1-Halometalation Mechanism: Insights from Quantum Chemical Calculations. ACS Catal. 2015, 5, 859.
18. G. Huang, M. Kalek, R.-Z. Liao, F. Himo*. Mechanism, Reactivity, and Selectivity of Iridium-Catalyzed C(sp3)-H Borylation of Chlorosilanes. Chem. Sci. 2015, 6, 1735.
19. G. Huang, M. Kalek, F. Himo*. Mechanism and Selectivity of Rhodium-Catalyzed 1:2 Coupling of Aldehydes and Allenes. J. Am. Chem. Soc. 2013, 135, 7647.
五、荣誉和奖励:
天津市高层次人才青年项目(2015)
天津大学-北洋青年骨干教师(2016)
天津大学“教书育人”青年先进工作者(2017)
天津市第十四届青年教师教学竞赛校内选拔赛理科组一等奖(2017)
天津大学2018届本科生毕业设计(论文)优秀指导教师(2018)
天津大学第十二届研究生“我心目中的十佳好导师”(2019)
天津大学沈志康奖教金(2020)
天津市优秀硕士学位论文指导教师(2022)
六、讲授主要课程:
有机化学、有机化学实验、计算机实习、多尺度分子计算机模拟
七、主持科研项目:
国家自然科学基金-面上项目(批准号:22073066,2021.1-2024.12)
国家自然科学基金-青年项目(批准号:21503143,2016.1-2018.12)
天津市自然科学基金-青年项目(批准号:16JCQNJC05600,2016.4-2019.3)
天津大学自主创新基金(2017.1-2018.12;2020.1-2020.12)
八、参编教材:
《有机化学(第六版)》赵温涛、郑艳、王光伟、马宁、黄跟平编;高等教育出版社;ISBN:978-7-04-052161-0。
《有机化学(第六版)学习指南》王光伟、聂晶、马宁等编;高等教育出版社;ISBN:978-7-04-054201-1。
《Klein's Organic Chemistry (Global Edition)》翻译版 郑艳、赵温涛、李珅、王光伟、黄跟平、聂晶译;高等教育出版社;ISBN:978-7-04-058683-1。
九、教改论文:
有机化合物命名原则(2017)的简化及在有机化学教材中的应用,黄跟平、赵温涛*,化学教育,2020,41,20-24.
十、社会服务:
1.《Chin. Chem. Lett.》青年编委和《化学试剂》编委
2. Nature Chem.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nature Commun.、ACS Catal.、J. Org. Chem.、Org. Lett.、Chem. Commun.、Org. Chem. Front.等期刊审稿人